Nebraska omicron cluster suggests faster symptom onset

Nebraska omicron cluster suggests faster symptom onset


Healthcare staff put together Covid-19 assessments at a Nomi Well being testing web site in Omaha, Nebraska, on Wednesday, Nov. 10, 2021.

Dan Brouillette | Bloomberg | Getty Pictures

An investigation right into a cluster of omicron infections in Nebraska suggests the closely mutated variant has a shorter incubation interval and causes comparable or milder signs in contrast with previous variants for people who find themselves vaccinated or beforehand contaminated, in accordance with the U.S. Facilities for Illness Management and Prevention.

The CDC on Tuesday launched findings from an epidemiological investigation into six omicron instances confirmed in a single family in Nebraska.

A 48-year-old man who returned to the U.S. on Nov. 23 from a convention in Nigeria skilled signs a day later and examined optimistic for the virus on Nov. 26. The person, who was unvaccinated and had a previous historical past of symptomatic an infection in 2020, reported he was not carrying a masks when he had shut contact with a masked particular person who was coughing on the worldwide convention on Nov. 20.

The person took an antigen check earlier than returning to the U.S. and the outcomes got here again detrimental on Nov. 21. Upon his return to the U.S., he was nonetheless asymptomatic and had shut contact with 5 members of his family in Nebraska with out carrying a masks on Nov. 23.

The 5 members of his family, at the very least one in all whom was as younger as 11 years outdated, developed signs Nov. 24-26 and subsequently examined optimistic. 4 of them had prior histories of symptomatic an infection in 2020, one in all whom was totally vaccinated with two Pfizer doses.

One other individual within the family was unvaccinated and had by no means examined optimistic for Covid earlier than. Nevertheless, that individual did have gentle higher respiratory signs in November 2020 earlier than the opposite members of the family first bought contaminated.

The CDC mentioned it took 33 to 75 hours, a median of about three days, for family members to indicate signs after publicity to the person who traveled, suggesting a shorter incubation interval with omicron. The median incubation interval for Covid is 5 days or extra, whereas the delta variant usually takes about 4 days for signs to indicate, in accordance with the CDC.

The family members who had been reinfected skilled fewer signs in contrast with their first infections in November 2020, in accordance with the CDC. Two of them reported fevers after an infection, none reported lack of style or odor.

The unvaccinated one that had not examined optimistic earlier than skilled cough, joint ache, congestion, fever and chills. No one within the family required hospitalization after testing optimistic for omicron and none of them had underlying well being situations or compromised immune techniques. These reinfected didn’t require hospitalization after their first infections in 2020 both.

The primary confirmed case of omicron was reported on Dec. 1 within the San Francisco space by California public well being authorities. The affected person had returned from a visit to South Africa. Nevertheless, the CDC subsequently discovered somebody who reported signs on Nov. 15 after worldwide journey, indicating that the variant might have arrived within the U.S. earlier.

Omicron was first recognized by South Africa and Botswana in November. The variant now represents 58% of sequenced instances within the U.S., whereas delta makes up about 41% of instances, in accordance with the CDC.

A rising physique of information from South Africa and the UK signifies that individuals don’t get as sick from omicron in contrast with the delta variant. The U.Ok. Well being Safety Company discovered that individuals contaminated with omicron had been 50%-70% much less prone to require hospitalization. South African scientists discovered that individuals contaminated with omicron had been 70% much less prone to develop extreme illness.

Nevertheless, the authors of the research cautioned in opposition to studying too deeply into the preliminary information, as a result of vaccination and immunity from prior an infection might have influenced the findings.

One other research from the U.Ok. Well being Safety Company discovered {that a} booster dose of Pfizer and BioNTech’s vaccine supplies 75% safety in opposition to symptomatic illness from omicron. South African information means that two doses of the Pfizer vaccine nonetheless protects in opposition to extreme sickness however is way much less efficient at stopping omicron an infection.

Within the U.S., new Covid instances are surging to close pandemic highs. The nation reported a median of greater than 237,000 day by day new instances for the seven-day interval ending Monday, up 66% over the previous week, in accordance with a CNBC evaluation of information from Johns Hopkins College.

Greater than 70,000 folks within the U.S. are presently hospitalized with Covid, up 3% over the previous week, in accordance with a seven-day common of information from the Well being and Human Companies Division as of Dec. 27.



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